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In Alzheimer's, the brain runs low on glutathione, its master antioxidant, before plaques and tangles appear. Refilling it is hard, since glutathione and NAC are barely absorbed. A new Pitt-led editorial makes

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TB-500 is a synthetic fragment of thymosin beta-4 (residues 17–23, sequence Ac-LKKTETQ) studied for its role in actin sequestration and cytoskeletal organization — specifically the regulation of G-actin to F-actin polymerization balance that governs cell morphology and migration