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Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia

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Neurons innervating the striatum, including dopaminergic neurons from the SNc–VTA regions, take up AA, which, in low-TH-expressing cells, the phenotype can switch to a dopaminergic one through TH synthesis

This may result in a fierce cycle of oxidative stress and challenges to detoxification