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But structural repair (collagen deposition, fiber organization, tensile strength recovery) requires 4 to 8 additional weeks

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Indeed, in a 2025 study, skin care products made with Lactobacillus ferment lysate were found to reduce facial erythema within two weeks,58 and another 2025 study observed that Lactococcus ferment lysate could reduce acne severity, sebum levels, and inflammatory factors on the skin.59 Reishi and shiitake extracts Reishi and shiitake mushrooms have also shown some utility in the skin care space