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4.5 Abnormalities of classical metabolic pathways In the mechanism of gemcitabine resistance, the functional defect of the nucleoside transporter hENT1 (human equilibrative nucleoside transporter 1) is the core link of the abnormality of the classical metabolic pathway

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Male Sprague-Dawley rats, weighing 200 to 250 gm, were used as the source of tendon fibroblasts in this study