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Moreover, activation of the HGF/c-Met system improves cognition (Akimoto et al., 2004)—an outcome that may reflect its ability to induce dendritic remodeling (Tyndall et al, 2007) and spur neural stem cell proliferation and differentiation (Nicoleau et al., 2009)

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Overall, AST demonstrates considerable potential as a neuroprotective agent in AD