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A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

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Curcumin has antioxidant properties, downregulates nuclear factor Kappa B (NF-κB) to inhibit pro-inflammatory cytokines, and activates AMP-activated protein kinase (AMPK) to promote fatty acid oxidation (Safari et al., 2023)