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ALA administration to HFD animals led to a decrease in the hypothalamic 8-isoprostanes (-42%) as compared to the HFD ALA- group and an increase in the cerebral cortex 8-isoprostanes when compared to CD ALA+ (+62%) and to the CD ALA- group

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To probe the enzymatic function of GlpQ1 and its role in PM remodelling we generated an in-frame clean genetic deletion of glpQ1 in H37Rv (D glpQ 1 strain) and performed unbiased global metabolomics paired with lipidomics

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