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The study established both acute and chronic PD mouse models using MPTP, demonstrating that hydrogen water at low and high concentrations (0.08–1.5 ppm) significantly reduced dopaminergic neuron loss and decreased the accumulation of oxidative markers, such as 4-HNE and 8-oxoG

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Tucker D, Lu Y, Zhang Q. From mitochondrial function to neuroprotection: an emerging role for methylene blue. Mol Neurobiol. 2018;55(6):5137-5153. doi:10.1007/s12035-017-0712-2. PMID: 28840449