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Iron metabolism is, in part, regulated by ferritin heavy chain (FTH1), which converts Fe²⁺ to Fe³⁺ and stores it in a redox-inactive form, and by STEAP-3, an endosomal ferrireductase that converts Fe³⁺ to Fe²⁺ to sustain the labile iron pool [22, 23]

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Plasma concentrations and genetic variation of matrix metalloproteinase 9 and prognosis of patients with cardiovascular disease