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Common considerations include: Injection site reactions such as redness or mild swelling Possible headaches or flushing shortly after dosing Water retention in some patients, especially with higher IGF-1 elevation Limited long-term human outcome data for both peptides in adult wellness use Need for baseline and follow-up bloodwork to track hormone levels safely Because controlled human outcome data remains limited for both peptides when used for fat loss, recovery, or anti-aging goals, working with an experienced clinic matters