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Systematic reviews suggest that acupuncture modulates neurotrophic factors (e.g., BDNF), neurotransmitters (e.g., 5-HT, dopamine), inflammatory cytokines, and the neuroendocrine system, exerting both antidepressant and anticonvulsant effects ( Further preclinical studies have demonstrated that acupuncture at Baihui (GV20), Yintang (EX-HN3), and other related acupoints significantly inhibits microglial polarization toward the pro-inflammatory M1 phenotype and reduces the expression of TNF- and IL-1 by suppressing the Toll-like receptor 4 (TLR4)/Myeloid differentiation primary response 88 (MyD88)/NF-B signaling cascade, thereby attenuating neuroinflammation (Li et al., 2024)
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BPC157:10mg
Some patients do well with oral B12