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Furthermore, in a rodent model of spontaneous hypertension and chemical disruption of NO bioavailability, l-citrulline restored levels of NO by increases l-arginine/asymmetrical dymethylarginine (ADMA) ratio [48,49,50]

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If someone is telling you NAC is "proven to restore ovulation in PCOS" or "as effective as metformin," they are repackaging a small set of smaller studies and integrative-practitioner observations as something stronger than it is